Hydroxypinacolone Retinoate (HPR) is a part of the vitamin A family of ingredients, and is classed as an ester of retinoic acid. This means it is able to bind directly with the retinoic acid receptors in our body, without the need for conversion first (a process all retinol derivatives undergo, which typically reduces their potency). 

Hydroxypinacolone retinoate is part of a family of ingredients also found on ingredients lists as retinol, retinaldehyde, Retinoic acid (aka tretinoin), encapsulated retinaldehyde, retinyl palmitate, retinyl propionate or retinyl retinoate (8x more powerful than retinol).

Renude

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This retinoid-based formula is a great option for you to target blemishes, post-blemish marks and fine lines. It contains two different types of retinoid, alongside soothing ingredients such as bisabolol to reduce any potential irritation.

Bisabolol is a naturally-occurring active found in the chamomile plant, although this can also be created synthetically. It’s key properties are as an anti-inflammatory and soothing agent, with some studies also showing it to have a brightening effect on the skin. Bisabolol is also a rich source of Panthenol (Vitamin B5), which acts as a humectant, meaning it draws water molecules towards it to plump and hydrate the area. Studies have also shown that bisabolol can enhance the penetration of other actives into the skin, so is great when used in combination with other actives designed to work at the basal layer of the epidermis, or in fact the dermis.

bisabolol

Hydroxypinacolone Retinoate (HPR) is part of the Vitamin A family, and is classed as an ester of retinoic acid. This means it is able to bind directly with the retinoic acid receptors in our body, without the need for conversion first (a process all retinol derivatives undergo, which typically reduces their potency). 

hydroxypinacolone retinoate

Vitamin A, aka Retinol, is one of the most well-researched actives used in skincare today. Retinol and all of its derivatives are broken down within the skin first into retinaldehyde, then into retinoic acid, the active form recognised by the body to trigger it’s skin benefits.

Retinoic acid (aka tretinoin) is the gold standard of anti-ageing and works in a number of ways. Firstly, it blocks the production of collagen-degrading enzymes, meaning collagen does not get broken down as quickly in the skin. After prolonged use (6M+), it has also been shown to stimulate the production of type I and type III collagen, reducing wrinkles and improving skin firmness. It has been shown to protect against UV-induced damage, as well as reducing the appearance of hyperpigmentation in the skin. Skin treated with retinoids is smoother, more even-toned, firmer and younger looking.

retinol

This natural berry is high in antioxidants, to help protect against free radical damage, and also has anti-inflammatory properties to soothe and calm.

tasmannia lanceolata fruit/leaf extract

Fight signs of ageing with The Ordinary Granactive Retinoid 2% Emulsion, a solution that combines two forms of next-generation Retinoid to help improve the appearance of ageing and acne-prone skin. The two Retinoids used are a Solubilized Hydroxypinacolone Retinoate (which has a multi-fold anti-ageing effect and is more efficient than Retinol), and pure Retinol in a protective capsule system which supports the delivery and efficacy of Solubilized Hydroxypinacolone Retinoate. The solution works to visibly fight signs of ageing without irritating the skin.

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I have chosen this nourishing retinol-based oil for your evening routine, to target visible ageing of the skin, which you mention as a concern.

solanum lycopersicum (tomato) fruit extract

Stem cells occur naturally within plants to help regenerate cells after stress or injury, and studies show this can encourage similar regenerating mechanisms in human skin. Tomato stem cells provide antioxidant protection to protect against free radicals, as well as acting as a chelating agent to sequester heavy metals which could result in damage, so overall this ingredient has great protective properties.

This water-free solution contains a 2% concentration of an advanced retinoid active complex called Granactive Retinoid that has been shown to offer better results against multiple signs of aging than retinol without any of the irritation and drawbacks common with retinol. Granactive Retinoid, an active technology from Grant Industries, is a solubilized system of Hydroxypinacolone Retinoate, a highly-advanced form of retinoid which is, in fact, a non-prescription ester of all-trans direct retinoic acid that offers a multi-fold better effect against signs of aging than retinol, retinyl palmitate and nearly all other forms of non-prescription retinoid.

I have chosen this serum for your evening routine to target the signs of ageing and congestion within the skin.

**Phase in slowly. Start with 1x per week, building up usage (if tolerated) to every night over several weeks. Avoid the corners of the mouth, the eye area and the neck.

Sodium hyaluronate is the sodium salt of hyaluronic acid (a polysaccharide which occurs naturally in the body), created to improve the ingredient stability. It works as an extremely powerful humectant, able to attract 1000x its own weight in water, to immediately plump and hydrate the area it is applied to. The body’s own production of hyaluronic acid slows with age, so supplementing this ingredient in topical formulations helps to support the skin’s natural moisture-binding, anti-ageing mechanisms.

sodium hyaluronate

Hyaluronic acid is a polysaccharide which occurs naturally in the body. Hyaluronic acid works as an extremely powerful humectant, able to attract 1000x its own weight in water, to immediately plump and hydrate the area it is applied to. The body’s own production of hyaluronic acid slows with age, so supplementing this ingredient in topical formulations helps to support the skin’s natural moisture-binding, anti-ageing mechanisms.

Garden of Wisdom's Granactive Retinoid 5% Serum contains 5% of Hydroxypinacolone Retinoate, an advanced retinoid which offers significant benefits against the multiple signs of ageing. Granactive Retinoid 5% Serum is a technology from Grant Industries providing 0.5% of an ester of All-Trans Retinoic Acid and is one of the most bio-available, non-prescription forms of Vitamin A. Granactive Retinoid provides an effective delivery system to protect skin against ageing when compared to retinol with little or no irritation. Granactive Retinoid Serum may also be of value in treating moderate to severe acne when other treatments have not worked effectively. Retinoids fight breakouts on face by normalising the removal of dead skin cells that clog pores leading to blackheads, whiteheads and pimples. pH 6.5 - 6.9.

Retinoids are clinically proven in treating both acne and ageing concerns. These mid-strength options are grerat for skin already acclimatised to retinoids.

Mid-strength retinoid serum picks

We consider Medik8 to be the Queen of retinoid innovation, and this serum does not disappoint. A great mid-strength option, it uses 0.06% encapsulated retinaldehyde, which has been shown to deliver results 11x faster than retinol, without any of the commonly associated side effects (dry, flaky skin, redness, irritation). The silky, lightweight creamy serum also includes glycerin, vitamin e and hyaluronic acid to hydrate the skin. Natural tonka bean extract gives it a delicate vanilla scent. Vegan.

A lightweight oil-based serum containing 0.6% pure retinol alongside antioxidant vitamin e in a jojoba oil base (jojoba is structurally very similar to the skin's own sebum, which means it absorbs well and does not clog pores). Fragrance free. Vegan.

This oil-based serum contains 5% Granactive retinoid (hydroxypinacolone retinoate for the geeks out there). This new generation retinoid has been shown to be as effective as prescription-only retinoic acid, without any of the associated negative side effects, and is optimised for maximum absorption into the skin. Fragrance free.

Cruelty free

UK made

Diverse founder

Female founder

Unfragranced

I have chosen this nourishing oil for your evening routine, to target visible ageing of the skin, which you mention as a concern.

cold pressed avocado) oil

Avocado oil is a rich source of fatty acids, which help to protect excess water loss through the skin’s surface, to keep it moisturised, soft and smooth. This oil also has antioxidant properties so helps to protect skin against free radical damage.

persea gratissima (extra virgin

vitis vinifera (organic

Resveratrol in a polyphenol most famously found in the skin of red grapes, but also occurs naturally in peanuts and certain fruits such as blueberries and cranberries. It is included in skincare for its powerful antioxidant abilities - with research showing it can protect against free radicals, as well as oxidative damage caused by UV.

PRODUCT DETAILS: A next-generation retinol oil that boosts the look and feel of skin plumpness, while improving the appearance of wrinkles, redness, and pores for visibly younger-looking skin.

HOW IT WORKS: Luna works throughout the night to deliver visibly youthful, luminous, even-toned skin in the morning. Trans-retinoic acid ester complex reduces the appearance of pores and wrinkles, while visibly improving the signs of premature aging: fine lines, uneven texture, age spots, dryness, and dullness. Balanced with blue tansy and German chamomile essential oils, both rich in soothing, blue azulene, visible redness and the signs of sensitivity are neutralized, for a calm, even-toned complexion.

I have chosen this potent anti-ageing treatment to target the key areas of ageing you mention are concerns for you: wrinkles, skin firmness, enlarged pores and pigmentation.

ceramide np

Ceramides are long chains of lipids, which occur naturally within the epidermis. Their function is to hold the skin cells together by creating a barrier against water-loss from the inside-out, and external aggressors from the outside-in. They make up almost 50% of our skins composition, but they can be depleted by UV, free radicals & pollution, and their production also naturally slows with age. This leads to an impaired skin barrier, which results in dry, rough skin with more visible wrinkling and redness. Applying ceramides topically can increase the levels of ceramides in the epidermis, and therefore supports the natural healthy functioning of the skin.

Tocopheryl acetate is a specific form of the fat-soluble Vitamin E, with improved stability vs. Tocopherol. Vitamin E is found naturally in our own skin, and it’s main benefit is to offer powerful antioxidant protection against pollution and free radical damage. It also helps to support our skin’s natural lipid barrier, which in turn improves the hydration levels within the epidermis, as water loss through the skin is minimised.

tocopheryl acetate

Vitamin E is a fat-soluble Vitamin contained in many plant oils, or can also be produced synthetically. Vitamin E is found naturally in our own skin, and it’s main benefit is to offer powerful antioxidant protection against pollution and free radical damage. It also helps to support our skin’s natural lipid barrier, which in turn improves the hydration levels within the epidermis, as water loss through the skin is minimised.

Urea is humectant ingredient found in the skin’s natural moisturising factor (NMF), making up around 7-8% of the total composition. Its humectant properties mean it can bind to water molecules in the atmosphere, drawing them to it, and in turn plumping and hydrating the skin. Research also shows that Urea has a mild exfoliating action on the skin, encouraging the removal of dead cells which results in smoother, healthier, more hydrated skin.

urea

yeast amino acids

Amino acids are the small building blocks that make up peptides, and proteins. Each amino acid has a unique structure, and as such plays a specific role within the body. There are around 20 different types considered to be most important for human health. In the outer layer of the skin, the stratum corneum, they are present in the ‘natural moisturising factors’, our skin’s own moisturising mechanism, and they help to support water transport between skin cells to keep our surface smooth and hydrated.

All ages and sensitive skin welcome: Helps minimise the signs of ageing you can see, and the ones you can’t see yet. Delivers an instant dose of retinol and a dose of retinol over time to minimise irritation and prolong benefits. Preventative and corrective retinol for all ages, and even tested safe for sensitive skin.

Hydroxypinacolone Retinoate

What is Hydroxypinacolone Retinoate?

What does Hydroxypinacolone Retinoate do?

Who is Hydroxypinacolone Retinoate good for?

Who should avoid Hydroxypinacolone Retinoate?

Hydroxypinacolone Retinoate

What is Hydroxypinacolone Retinoate?

What does Hydroxypinacolone Retinoate do?

Who is Hydroxypinacolone Retinoate good for?

Who should avoid Hydroxypinacolone Retinoate?

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